valium half life elderly

The risk is increased in those taking concomitant sedatives including alcohol and in the elderly. The half-life of Valium is approximately 48 hours.

Diazepam Valium Alcohol Are They Safe To Mix Effects Withdrawal

In full term infants elimination half-lives around 30 hours have been reported with.

. A persons age determines how their body eliminates Valium. Valium is a long-acting benzodiazepine with a half-life of up to 48 hours which means it can be active in the body for a few days. In children 3 - 8 years old the mean half-life of diazepam has been reported to be 18 hours.

Furthermore alterations in phar. Longer half-lives such as chlor-diazepoxide diazepam and flu-razepam are more likely to accumu-late in the body and cause prolonged sedation 10. Dosages that may have a therapeutic effect for.

In children 3 - 8 years old the mean half-life of diazepam has been reported to be 18 hours. Diazepam is subject to Schedule IV control under. Drug Abuse And Dependence.

Valium has a relatively long half-life. Many benzodiazepines have a half-life of several hours. It takes approximately 20 to 54 hours for half of the drug to.

Active metabolites may remain in the body for as long as 20-100 hours after use. Following intravenous administration the half-life and volume of distribution of 14C-labelled diazepam in the elderly were approximately twofold greater than corresponding estimates in. Valium is generally prescribed to be taken in doses between.

In full term infants elimination half-lives around 30 hours have been reported with. The half-life is increased by approximately 1 hour for each year of age beginning with a half-life of 20 hours at 20 years of age as the volume of distribution is increased and. Adverse reactions to benzodiazepines are more common among elderly patients and occur more frequently with advancing age.

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